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Subjective Units of Distress Scale (SUDS) is a psychometrically valid and reliable outcome measure for the assessment of anxiety in social anxiety disorder (SAD) clinical trials
8 Dec 2023 Download (252Kb) (252Kb)
Development of an Improved Oral Tablet Formulation of BNC210, a Negative Allosteric Modulator of the α7 nAChR, Suitable for Evaluation as an Acute Treatment for Social Anxiety Disorder
5 Dec 2022 Download (1.7Mb) (1.7Mb)
Pharmacometrics Analysis and Drug Reformulation of BNC210 to Optimize its Evaluation in a Phase 2 Trial in PTSD Patients
6 Dec 2022 Download (2.6Mb) (2.6Mb)
Cholinergic modulation of disorder-relevant human defensive behaviour in generalised anxiety disorder
1 Jan 2021 Download (957Kb) (957Kb)
Cholinergic Modulation of Disorder-Relevant Neural Circuits in Generalized Anxiety Disorder
1 May 2020 Download (595Kb) (595Kb)

α7 Receptor PAM

Discovery of BNC375, a Potent, Selective, and Orally Available Type I Positive Allosteric Modulator of α7 nAChRs
31 Dec 2018 Download (943Kb) (943Kb)