OUR EXECUTIVE TEAM

Spyridon “Spyros” Papapetropoulos M.D., PhD

President & Chief Executive Officer

Dr Papapetropoulos is an experienced biopharmaceutical executive, a recognized neuroscientist/neurologist, and change agent with a 25-year career focused on CNS disorders. He held various positions of increasing responsibility at CNS-focused start-up/small, medium specialty and large biopharma companies. Prior to joining Bionomics Ltd. he served as Chief Medical Officer of Vigil Neuroscience Inc, (NASDAQ: VIGL), as Chief Development Officer, and SVP, Head of Clinical Development at Acadia Pharmaceuticals Inc (NASDAQ: ACAD)., CEO at SwanBio Therapeutics, and EVP of Research & Development and Chief Medical Officer at Cavion Inc. Before Cavion, he held senior/executive positions at Biogen Inc., Allergan plc, Pfizer Inc., and Teva Pharmaceuticals Inc. Spyros has filed multiple INDs and has overseen a broad spectrum of CNS biopharmaceutical development programs (small molecules, biologics, gene therapy), leading to successful regulatory filings (20+ INDs and multiple NDAs/BLAs) and new product approvals and launches worldwide.

Dr Spyridon “Spyros” Papapetropoulos, M.D., President & CEO — Spyridon “Spyros” Papapetropoulos, M.D., PhD – President & CEO

Tim Cunningham MBA

Chief Financial Officer

Mr. Cunningham has served as a Chief Financial Officer Consultant at Danforth, a strategic finance and operations firm with a focus on life sciences companies, since September 2020, where he provides chief financial officer consulting services to both public and private pharma and biotechnology companies. Prior to joining Danforth, Mr. Cunningham served as Chief Financial Officer at Organogenesis (NASDAQ:ORGO), where he took the company public and raised over US$250M in equity and debt financing to facilitate the company’s growth. He has held leadership positions with several different public and private companies over the course of his career, which began at KPMG in NY followed by PwC Boston. Mr. Cunningham holds an MBA from Boston University, a BS in Accounting from Boston College and is a CPA in the state of Florida.

Mark A. Smith M.D., Ph.D

Chief Medical Officer

Dr Smith was Chief Medical Officer at VistaGen Therapeutics, where he led the clinical development of drug candidates in the areas of major depression, social anxiety disorder, and depression through all phases of development. Previously, Dr. Smith served as the Clinical Lead for Neuropsychiatry at Teva Pharmaceuticals, where he was accountable for the strategy and clinical development of neuropsychiatric drugs with a focus on schizophrenia, sleep disorders, and agitation. He also held a range of director positions, including as Executive Director of Clinical Development at AstraZeneca Pharmaceutical Company, where he led the development of several novel chemical entities targeting treatment-resistant depression, anxiety, and schizophrenia. Dr. Smith was also Senior Director of Experimental Medicine of Global Clinical Development and Innovation at Shire Pharmaceuticals and Senior Investigator and Principal Research Scientist of CNS Diseases at DuPont Pharmaceuticals. Prior to joining the pharmaceutical industry, he served as a Senior Staff Scientist of the Biological Psychiatry Branch and Senior Staff Fellow of the Clinical Neuroendocrinology Branch at the U.S. National Institute of Mental Health (NIMH). Dr. Smith received his Bachelor’s degree and Master of Science from Yale University, his Doctor of Medicine and Doctor of Philosophy in Physiology and Pharmacology from the University of California, San Diego, and completed his residency in the Department of Psychiatry at Duke University Medical Center. He currently serves on the National Institute of Mental Health Translational Neuropsychopharmacology Task Force.

Liz Doolin MSc

Senior Vice President Clinical Development

Ms Doolin has over 25 years international experience in drug discovery, clinical and life sciences research. She joined Bionomics Limited in 2008 to lead the early clinical development program for BNC210, a small molecule with therapeutic potential for anxiety disorders, and trauma and stressor-related disorders including PTSD. Ms Doolin currently leads Bionomics’ clinical programs across central nervous system disorders and oncology, including three novel investigational drugs in Phase 1 and 2 clinical development. In addition to her extensive clinical research experience in Australia, Ms Doolin has a strong immunology and biotechnology research background, as well as biopharmaceutical development and GMP manufacturing experience, gained in New Zealand and the UK.

Liz Doolin – Senior Vice President of Clinical Development

Julie Kerner PhD

SVP Business Operations

Dr Kerner is a biotech leader and enterprise thinker with 15+ years of drug development from early research through commercialization. Under her leadership, companies created portfolio and platform strategies, filed 10+ IND/CTAs, conducted proof of concept and Phase 3 trials, and launched multiple therapeutics. Most recently, Julie worked at Fulcrum Therapeutics and Aliada Therapeutics driving pipeline strategy and program leadership. Prior to that, she worked at AVROBIO, Wave Life Sciences, and Biogen working across R&D, Marketing, and early product planning. Before she joined industry, Julie earned a PhD in Neuroscience at Tufts Medical School and was a market analyst at Decision Resources, writing over 10 reports on neurodegeneration, psychology, and pain. Julie is committed to patient centricity and advocacy, sitting on the boards of Newton Wellesley Hospital, National Braille Press, and the US Neuroacanthocytosis advocacy, Inc.

Julie Kerner PhD, SVP Business Operations

Matthew Brennan MSc, MBA

VP Business Development and Scientific Evaluation

Mr Brennan is a cross-functional biotech leader and entrepreneur with well over a decade of drug discovery and business development experience. Prior to joining Bionomics, he was part of the founding team of Vigil Neuroscience where he led business development and played a critical role in the company’s strategic growth, private and public financings and the advancement of the programs into the clinic. Matt worked in management positions at Ipsen as part of the Global External Innovation and Partnering team where he was involved in several successful transactions. Matt’s career began as a scientist where he made significant contributions to the discovery and development of next generation therapeutics such as the KRAS inhibitors currently being developed by Revolution Medicines, Fog Pharma’s Beta-catenin/TCF4 inhibitor and several immunology antibody and nanobody programs at Sanofi. Matt graduated with honors from Northeastern University earning his B.Sc. in Cell and Molecular Biology with minors in Psychology and Business Administration. Matt earned his M.B.A. from Babson College, a certificate in General Management from Stanford University Graduate School of Business and is an author and inventor on over 10 publications and patents.